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|Title: ||Implementation of a Functional Semantic Similarity Measure between Gene-Products|
|Authors: ||Couto, Francisco M.|
Silva, Mário J.
Coutinho, Pedro M.
|Issue Date: ||Nov-2003 |
|Publisher: ||Department of Informatics, University of Lisbon|
|Series/Report no.: ||di-fcul-tr-03-29|
|Abstract: ||Sequence similarity is a common technique to compare gene-products. However, many applications need to compare gene-products based on what they do, not how they are. Most gene-products are being annotated with terms describing their biological function. These terms are defined in biological ontologies. This makes it possible to implement similarity measures between gene-products based on their behavior. We define FuSSiMeG, a functional similarity measure between gene-products that compares the semantic similarity between the terms in their annotations. Software available from http://xldb.fc.ul.pt/rebil/ssm/|
|Appears in Collections:||Technical Reports|
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